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Cara Plott: ‘Are you OK?’ A med student’s plea for action to stop gun violence

Cara Plott: ‘Are you OK?’ A med student’s plea for action to stop gun violence

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By Cara Plott, a second-year medical student at Johns Hopkins University School of Medicine in Baltimore. I am sick of needing to text my friends and family to ask whether they have been shot. On Nov. 7, my friend traveled to Thousand Oaks, California, to visit her family. Late that night, a gunman shot and(...)

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Never a Dull Moment in Cardiology

Never a Dull Moment in Cardiology

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If it sounds like it’s too good to be true, then it probably is. This proverb may come across as pessimistic; however, it seems to be ringing true for Piero Anversa. Anversa made waves in the field of cardiology with his studies on cardiac muscle regeneration and the proposed use of cardiac stem cells to(...)

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From Crisis to Consensus: Guidelines Aim to Reduce Over-Prescribing of Abused Drugs

From Crisis to Consensus: Guidelines Aim to Reduce Over-Prescribing of Abused Drugs

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Every day, 115 Americans are killed by opioid overdose. That this number is so strikingly high underlines the language of ‘“epidemics” and “emergencies” in politicians’ speeches and newspaper headlines. Thousands of articles and millions of research dollars have become components of a concerted effort to understand, quantify and alleviate the opioid epidemic in the United(...)

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The Colorful World of Cancer Drug Discovery

The Colorful World of Cancer Drug Discovery

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Melanoma cells stained with PTRF (in red), RPA194 (in green) and nucleus stained in blue. RPA194 is the main subunit of the RNA polymerase I (POL 1) enzyme. Our lab discovered a first-in-class small molecule that inhibits POL 1 enzyme and causes the destruction of RPA194 protein. Here, we are investigating how these proteins are(...)

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Do You Want to Write for Us?

Do You Want to Write for Us?

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Our medical students, residents, postdocs and fellows have a lot to share — from daily life in the classroom, tips on surviving residency, new research that is pushing the boundaries of science and patient care, to the best places to grab a bite in Baltimore, they share it here. If you have a love of(...)

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Landmark RNAi-Based Therapy Achieves Clinical Success

Landmark RNAi-Based Therapy Achieves Clinical Success

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DNA serves as a blueprint for the protein repertoire that comprises the human body and its functions. To construct these proteins while also ensuring that its DNA remains safely tucked away in the nucleus, the cell generates disposable and short-lived copies of its active genes, called messenger RNA (mRNA). An array of molecular machines then(...)

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Targeting Diabetes with a High-Fiber Diet: It’s All in Your Gut!

Targeting Diabetes with a High-Fiber Diet: It’s All in Your Gut!

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Right this moment, your gastrointestinal tract is crammed with a vast number of different microbes, together referred to as the human gut microbiota. Don’t be too alarmed though, as this complex gut microbial ecosystem maintains a mutual and beneficial relationship with you. Given the bad reputation some bacteria have as being infectious and antibiotic-resistant, you(...)

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