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Persistent Parasite Proteins: How Protein Clearance in Malaria Infection Can Impact Diagnostics

Persistent Parasite Proteins: How Protein Clearance in Malaria Infection Can Impact Diagnostics

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Finding new treatments for infectious diseases is often the focus of clinical research, but recent research has demonstrated the importance of both developing and improving diagnostic tools in the fight against malaria. Malaria is a disease caused by the parasite Plasmodium falciparum, and mosquitoes spread it. In 2017, there were over 219 million cases of(...)

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When the Consequences of Sweeteners Are Not Sweet

When the Consequences of Sweeteners Are Not Sweet

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Coke, Pepsi, Dr. Pepper, Sprite, Sunkist, Mountain Dew, Sunny D, Brisk, Fanta, Kuat, Capri Sun and others — what do these drinks have in common? They’re all sugar-sweetened beverages. Sugar-sweetened beverages, or sugary drinks, are composed of any liquid sweetened with one or more forms of sugars, and they are the main source of added(...)

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Partnering Toward Discovery: A Focus on Inclusion Body Myositis

Partnering Toward Discovery: A Focus on Inclusion Body Myositis

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Many people are not familiar with a rare disease called inclusion body myositis (IBM). Most have never heard of it. On Jan. 22, 2019, Harry Benjamin Larman and students Janelle Montagne, Sahana Jayaraman and Kyla Britson presented their clinical and basic science research on IBM at the first event in this year’s Partnering Toward Discovery(...)

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Engineering Magic Bullets for Pancreatic Cancer

Engineering Magic Bullets for Pancreatic Cancer

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In a 1909 manuscript titled “Ueber den jetzigen Stand der Chemotherapie” (“About the Current State of Chemotherapy”), Nobel laureate Paul Ehrlich proclaimed, “We must learn to aim in a chemical sense.” What did he mean? Ehrlich was referring to his “magic bullet” theory of chemical specificity, the observation that certain drugs can eliminate disease-causing entities(...)

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Fuggetaboudit: Is Forgetfulness a Vice or a Virtue?

Fuggetaboudit: Is Forgetfulness a Vice or a Virtue?

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Where are my keys? What’s the name of that actor again? Did she say 3 or 4 o’clock? Forgetfulness is a part of life, albeit often an inconvenient one. If you find yourself wishing you would never forget anything, you may want to reconsider. Neuroscientists are beginning to uncover the molecular mechanisms of forgetting. With(...)

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The Relationship Between Age and Blood Pressure: Another Way Your Lifestyle Can Impact Heart Health

The Relationship Between Age and Blood Pressure: Another Way Your Lifestyle Can Impact Heart Health

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Many of us have likely experienced recent high blood pressure. Whether it’s from well-meaning but very inquisitive relatives, or the winding lines at the airport, most of us are acquainted with a temporary rise in blood pressure under stress. And unfortunately, high blood pressure (BP) is a common chronic issue for millions of people worldwide.(...)

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Thinking Outside the Brain

Thinking Outside the Brain

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Genetics began in the garden — Mendel’s pea experiments revolutionized and developed the field and principles we know and study today. Similarly, my scientific journey began with plants. In college, I studied the model organism Chlamydomonas reinhardtii, which is unique in its ability to thrive in total darkness, whereas most plants rely on photosynthesis. My(...)

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