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Advancing Glioblastoma Research: A Tale of Two Superheroes

Advancing Glioblastoma Research: A Tale of Two Superheroes

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Glioblastoma research is similar to superhero film plots. How, you may ask? If each superhero represents a different treatment drug, then we as researchers want to cause destruction of the cancer cells with the least number of superheroes possible. This is because we wouldn’t want patients to need to take a large cocktail of treatments(...)

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A New Blood Test Tries to Detect Cancer Sooner

A New Blood Test Tries to Detect Cancer Sooner

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A patient develops symptoms that cannot be explained. The doctor orders a myriad of tests to discern the cause. If cancer is suspected, the patient may go through a painful and sometimes invasive biopsy procedure to sample the tissue in question. But what if a simple blood draw could be used instead? This is the(...)

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Fresh or Frozen Embryos? Equal Live-Birth Rates Among Infertile Women

Fresh or Frozen Embryos? Equal Live-Birth Rates Among Infertile Women

Posted by  | Did You See This?, Recently Published

About 40 years ago (July 1978), Louise Joy Brown was born at Oldham General Hospital in England, weighing 5 pounds, 12 ounces. This birth may sound like any ordinary baby story, but the conception and delivery of Louise, the first human conceived through in vitro fertilization (IVF), symbolized the possibility of having children for women(...)

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Using Epigenetics to Fight Tumors

Using Epigenetics to Fight Tumors

Posted by  | Perspectives in Research, Recently Published

While the word cancer treatment may identify everything from chemotherapy to radiation, there is significant variance between the type of cancer and its responsiveness to even the most promising therapies. That has been precisely the case for the α-PD-1 immunotherapy treatment. While it has shown remarkable efficacy in patients diagnosed with lung cancer, other types(...)

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What Does Dopamine Really Do?

What Does Dopamine Really Do?

Posted by  | Perspectives in Research, Recently Published

You’ve probably heard of dopamine before. Dopamine is a neurotransmitter—a chemical in the brain responsible for conveying information from one cell to another. It has made quite a name for itself because all of our favorite things—eating delicious food, seeing the person you love, hearing a good song come on, getting a gift, winning a(...)

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Out with the Old, in with Repaired Joints

Out with the Old, in with Repaired Joints

Posted by  | Perspectives in Research, Recently Published

Osteoarthritis (OA) is not only the most common chronic condition of the joints, but also the most common type of arthritis, affecting approximately 27 million Americans.1 The prevalence of OA increases with age,2 and elderly patients experience swelling, pain and decreased mobility. Currently, there is no cure for this degenerative joint disease, and the only(...)

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A Revelation About DREADDs: A New Neuroscience Technique with Promise for Clinical Psychiatric Treatment

A Revelation About DREADDs: A New Neuroscience Technique with Promise for Clinical Psychiatric Treatment

Posted by  | Perspectives in Research, Recently Published

In an essay I published last year for the Lasker Essay Contest (and republished in our blog), I described optogenetics and chemogenetics, two technologies recently developed for basic neuroscience research that have the potential to improve the way we treat psychiatric illness. The major drawback to drugs currently prescribed for diseases such as depression, PTSD,(...)

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Smarter Antimalarial Use: Altering Drug Duration to Improve Efficacy

Posted by  | Perspectives in Research, Recently Published

Fighting malaria is getting harder, with rising rates of drug resistance and drug tolerance making it more difficult for doctors to effectively cure patients. Drug resistance is distinct from drug tolerance, in that a resistant microbe can survive even high doses of a particular drug, while tolerant microbes are able to replicate in the drug’s(...)

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