I remember the day I first met Carolina Montano, a fellow student in the Johns Hopkins M.D./Ph.D. program. It was toward the beginning of my first year in medical school. We were both at a dinner for M.D./Ph.D. interviewees, and, as with many conversations between medical students, we inevitably began to discuss our classes.

Photo of Carolina Montano in the lab.

Carolina was talking about her second-year lectures: “I am amazed by how much new information we can learn every single day!” Then, she and several second-year students began an animated conversation about one of the diseases in their lectures. I was immediately impressed by how much information Carolina seemed to know and by her enthusiasm for medicine. More recently, I have witnessed this same passion in a scientific context; we share a research interest in the topic of neuronal epigenetics.

Carolina was born in Barranquilla, Colombia, and came to the United States at the age of 20. Although she had attended three years of medical school in Colombia, she and her family were forced to flee to the U.S. under political asylum. When she first arrived in Florida, her English was poor. Hoping to improve her chances of returning to medical school one day, she enrolled in English-as-a-second-language classes at Miami-Dade College while working odd jobs.

Encouraged by her mentors at the community college, Carolina enrolled at Brigham Young University to study neuroscience and molecular biology. She was able to join a lab her sophomore year and increased her exposure to different techniques and laboratories by spending her summers doing research internships at Mayo Clinic and National Institutes of Health (NIH).

She excelled. After graduating summa cum laude, Carolina worked for two years at the National Institute of Arthritis and Musculoskeletal and Skin Diseases on an NIH scholarship. She then entered the Johns Hopkins M.D./Ph.D. program and the human genetics graduate program. For her thesis work, Carolina developed a statistical method to adjust for cellular composition in the human brain to determine which DNA methylation signals originate from neuronal versus non-neuronal cells1. Carolina is also working to characterize DNA methylation patterns in the brains of people who have schizophrenia.

Although Carolina is still at the beginning of her career, she already serves as a role model, especially for young Hispanic females interested in science and medicine.

“I love talking about science and teaching, to children and adults alike, as scientific knowledge is a powerful tool to live a better life and create a fair society," Carolina says. "People empowered by knowledge can make better decisions about their health, that of their children and the representatives they elect to lead them. Latinas are underrepresented in science and medicine, and if I can help inspire anyone to pursue the physician scientist path, I am happy to help them get there.”



1. Montaño CM, Irizarry RA, Kaufmann WE, Talbot K, Gur RE, Feinberg AP, Taub MA. 2013 Aug 30. Measuring cell-type specific differential methylation in human brain tissue. Genome Biol.


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