Melanoma cells stained with PTRF (in red), RPA194 (in green) and nucleus stained in blue. RPA194 is the main subunit of the RNA polymerase I (POL 1) enzyme. Our lab discovered a first-in-class small molecule that inhibits POL 1 enzyme and causes the destruction of RPA194 protein. Here, we are investigating how these proteins are(...)
About Jin-Yih Low
Posts by Jin-Yih Low:
The F-Word in Metastatic Prostate Cancer
A recent study, published in Nature Genetics, has found an interesting new link between the F-word and metastatic prostate cancer. Before you let your imagination run wild, this is not the four-letter F-word but the other F-word — fat. Fat is an important constituent of all living cells, as it is a critical component of(...)