Perspectives in Research

Who Has Time to Sleep?

Who Has Time to Sleep?

Posted by  | A Day in the Life, Perspectives in Research

At the proverbial watercooler in teaching hospitals across the world, one hears remarkably similar refrains: “This patient is back again,” “I have no idea why my experiment failed this time” and, most universally, “I’ve only slept three hours in the past two days!” Medical trainees often view sleep deprivation as a badge of honor, one(...)

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Gene Editing Under Fire

Gene Editing Under Fire

Posted by  | Perspectives in Research

CRISPR/Cas9 gene editing is the hottest new technology being used by molecular biologists and geneticists around the world. The method, first developed in prokaryotes in a collaboration between Jennifer Doudna’s group at University of California, Berkeley and Emmanuelle Charpentier’s lab at the Pasteur Institute in June 2012, allows targeted editing of the genomes of living(...)

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At the Vanguard of the Psychedelic Renaissance

At the Vanguard of the Psychedelic Renaissance

Posted by  | Did You See This?, Perspectives in Research

A priest, a minister and a rabbi walk into Johns Hopkins Bayview Medical Center to ingest psilocybin, the active ingredient in hallucinogenic mushrooms. Although this probably sounds like the beginning of a great joke, new advancements in the field of psychedelic medicine are no laughing matter. After nearly 50 years of prohibition, academic studies and clinical(...)

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Nobel Prize Winning Research May Lead to New Therapies for Cancer, Alzheimer’s

Nobel Prize Winning Research May Lead to New Therapies for Cancer, Alzheimer’s

Posted by  | Did You See This?, Perspectives in Research

Yoshinori Ohsumi of the University of Tokyo was recently awarded the 2016 Nobel Prize in Physiology or Medicine for his work in mechanisms for autophagy. What is autophagy? From the Greek roots “auto,“ or self, and “phagia,” or eating, the word literally means self-eating. In cell biology, autophagy describes the way that cells recycle unneeded(...)

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Cancer Drug Shows Surprising Potential as Parkinson’s Treatment

Cancer Drug Shows Surprising Potential as Parkinson’s Treatment

Posted by  | Perspectives in Research, Recently Published

Parkinson’s disease is a neurodegenerative condition caused by the death of dopamine-producing cells in a region of the brain called the substantia nigra, which leads to disruptions in neural circuits controlling motor function. Although the cause of this inappropriate cell death is largely unclear, one hypothesis is that it is due to the abnormal aggregation(...)

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Tasmanian Devils Evolve to Combat Contagious Cancer

Tasmanian Devils Evolve to Combat Contagious Cancer

Posted by  | Perspectives in Research

Australia is home to some of the deadliest creatures on the planet, including venomous snakes, poisonous spiders and hungry sharks. The Tasmanian devil may not be toxic, but the species is known for its vicious behavior. The carnivorous marsupial may look cute and cuddly, but its sharp teeth can take down a kangaroo. Unfortunately, feasting(...)

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