Perspectives in Research

Engaging Medical Students in Outpatient Clinics

Engaging Medical Students in Outpatient Clinics

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As a fourth-year medical student at Johns Hopkins, I have had the privilege of working with attending physicians in a number of outpatient clinics. My roles in the clinic have varied. In most clinics, I see the patient independently, take a history, and perform a physical exam. I then describe the course of the illness,(...)

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In Search of a Cure for Tissue Injury: The Rise of Mesenchymal Stem Cells in Regenerative Medicine

In Search of a Cure for Tissue Injury: The Rise of Mesenchymal Stem Cells in Regenerative Medicine

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Regenerative medicine has been dubbed the vanguard of 21st-century health care. This emerging field places an emphasis on curing rather than treating injured or impaired tissues, and seeks to repair damaged tissues in vivo (in the living body) using techniques that trigger cells’ intrinsic healing ability. In the event that the body is unable to(...)

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Double Duty: Repurposing Drugs for Novel Cancer Treatment

Double Duty: Repurposing Drugs for Novel Cancer Treatment

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What do an anti-parasitic drug used to treat pinworms and a frequently used anti-malarial drug have in common? According to recent studies from the labs of Johns Hopkins and University of Kentucky investigators, both mebendazole and chloroquine could be promising medicines to combat cancer. Mebendazole has been in use as an anti-helminthic drug since 1971.(...)

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From ‘Devil’s Lettuce’ to Prescription Drug: The Acceptance of Medical Marijuana

From ‘Devil’s Lettuce’ to Prescription Drug: The Acceptance of Medical Marijuana

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Medical marijuana, for years a controversial pipe dream throughout the United States, is embroiled in an entirely new debate in 2017. For decades, the discussion over legalized marijuana usage has centered on ethics and morality, conflicting desires between freedom and protection. These arguments are still robust today, but the terms have shifted — from medical(...)

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Bugs Resistant to Drugs: What Can We Do?

Bugs Resistant to Drugs: What Can We Do?

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In September 2016, a Nevada woman died of a bacterial infection. The woman, in her 70s, had been hospitalized previously in India due to a fracture of her right leg, which led to bone infections and more subsequent hospitalizations. During these infections, she almost certainly received antibiotics to help her recover, especially given that in(...)

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Uncovering How a Diabetes Drug Slows Cancer Growth

Uncovering How a Diabetes Drug Slows Cancer Growth

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What do a relatively unknown gene, a well-known signaling pathway and nuclear transport have in common? They’re all part of how diabetes and cancer drug metformin works. Metformin is a widely used type 2 diabetes drug that lowers glucose levels and sensitizes cells to insulin. Metformin’s mechanism has been long sought after, and studies into(...)

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Breaking Down Where the Money Goes: Personal and Public Health Care Spending in the United States

Breaking Down Where the Money Goes: Personal and Public Health Care Spending in the United States

Posted by  | Perspectives in Research, Recently Published

The United States spends more money on health care than any other country — $2.9 trillion in 2014, or about $9,110 per person. Spending continues to increase. With the arrival of the new Trump administration, the debate on health care costs is heightening. In preparation, let’s take a closer look at U.S. health care costs(...)

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New Frontiers in Major Depressive Disorder Treatment

New Frontiers in Major Depressive Disorder Treatment

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Major depressive disorder (MDD) afflicts more than 250 million people worldwide and is the most common source of disability for Americans. In addition to counseling and talk therapy, there is a veritable alphabet soup of medications, from amitriptyline to venlafaxine, currently prescribed to treat MDD. Each class of antidepressant acts on an individual or combination(...)

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