Perspectives in Research

Sleep: Our Panacea

Sleep: Our Panacea

Posted by  | Did You See This?, Perspectives in Research

Humans and animals share the most basic drives in life: the need for food and water, and the urge to procreate. Yet only humans have built a modern world in which these drives seem to cause more problems than they solve. Bookstores worldwide have dedicated whole sections to literature about reconciling your natural desires with(...)

More

What Does Dopamine Really Do?

What Does Dopamine Really Do?

Posted by  | Perspectives in Research, Recently Published

You’ve probably heard of dopamine before. Dopamine is a neurotransmitter—a chemical in the brain responsible for conveying information from one cell to another. It has made quite a name for itself because all of our favorite things—eating delicious food, seeing the person you love, hearing a good song come on, getting a gift, winning a(...)

More

Collaborations with Industry Strengthen Academic Research

Collaborations with Industry Strengthen Academic Research

Posted by  | Perspectives in Research

Medical research is not only conducted by professors in the hallowed halls of educational institutions. Other notable research bodies include privately funded research institutions, pharmaceutical companies, government, and nonprofit organizations. Industry labs have a targeted approach, often searching for a drug to treat a specific disease or to address a particularly lucrative problem in medical(...)

More

Out with the Old, in with Repaired Joints

Out with the Old, in with Repaired Joints

Posted by  | Perspectives in Research, Recently Published

Osteoarthritis (OA) is not only the most common chronic condition of the joints, but also the most common type of arthritis, affecting approximately 27 million Americans.1 The prevalence of OA increases with age,2 and elderly patients experience swelling, pain and decreased mobility. Currently, there is no cure for this degenerative joint disease, and the only(...)

More

A Revelation About DREADDs: A New Neuroscience Technique with Promise for Clinical Psychiatric Treatment

A Revelation About DREADDs: A New Neuroscience Technique with Promise for Clinical Psychiatric Treatment

Posted by  | Perspectives in Research, Recently Published

In an essay I published last year for the Lasker Essay Contest (and republished in our blog), I described optogenetics and chemogenetics, two technologies recently developed for basic neuroscience research that have the potential to improve the way we treat psychiatric illness. The major drawback to drugs currently prescribed for diseases such as depression, PTSD,(...)

More

Smarter Antimalarial Use: Altering Drug Duration to Improve Efficacy

Posted by  | Perspectives in Research, Recently Published

Fighting malaria is getting harder, with rising rates of drug resistance and drug tolerance making it more difficult for doctors to effectively cure patients. Drug resistance is distinct from drug tolerance, in that a resistant microbe can survive even high doses of a particular drug, while tolerant microbes are able to replicate in the drug’s(...)

More

Ecstasy and Agony: Accepting MDMA-Assisted Psychotherapy as a Breakthrough PTSD Treatment

Posted by  | Perspectives in Research, Recently Published

For the majority of the population, MDMA, or ecstasy, is simply an illegal drug, its use exclusive to underground dance clubs and its abuse the purview of the police. However, a small group of psychopharmacological researchers and advocates have been touting this compound as the next major frontline treatment for a variety of troubling psychological(...)

More

Everyday Antibiotics May Reveal New Therapies to Treat Your Breast Cancer

Everyday Antibiotics May Reveal New Therapies to Treat Your Breast Cancer

Posted by  | A Day in the Life, Perspectives in Research

New therapies to treat metastatic breast cancer may lie within one of the most commonly used agents in health care across the world: antibiotics. Sonal Chaudhari, a second-year medical student at the Johns Hopkins University School of Medicine, recently spent her summer working under Richard Jones, director of the Bone Marrow Transplant Program, co-director of the(...)

More