Perspectives in Research

Solving the Scientific Reproducibility Crisis

Posted by  | Perspectives in Research

In an ideal world, reproducibility is a cornerstone of scientific research. The scientific method should provide conclusions that are as close to the truth as possible. In reality, reproducibility of results is a constant worry in scientific research. According to a recent survey by Nature, scientific irreproducibility is at a crisis level. The inability to(...)

More

Prostate Cancer Therapy Linked to Depression

Posted by  | Perspectives in Research, Recently Published

A recent study by researchers from Harvard, MD Anderson and Weill Cornell, published in the Journal of Clinical Oncology, showed an association between a common treatment for locally advanced prostate cancer and clinical depression. These results are part of a broader conversation about how prostate cancer is treated and could impact the way that clinicians(...)

More

Modern Neuroscience has the tools to treat psychiatric illness

Posted by  | Honor Roll, Perspectives in Research, Recently Published

The following submission is the first place winner of The Albert and Mary Lasker Foundation 2016 essay contest. You can read the original posting here.  Modern medicine has worked miracles: we have cured infectious diseases with vaccines, replaced failing organs with transplants, converted many cancers from death sentences into treatable conditions. But one area has(...)

More

How Lithium Treats Bipolar Disorder

Posted by  | Perspectives in Research

Lithium is a first-line treatment for patients with bipolar disorder, which is characterized by mood swings between mania and depression. Although widespread use of lithium to treat mania began around the mid-20th century, we still know relatively little about the compound’s mechanism of action. And we know even less about why lithium fails to treat(...)

More

How Genetics Can Inform Future Missions to Mars

Posted by  | Events and Happenings, Perspectives in Research

On May 3, I and four other Johns Hopkins students volunteered with the Personalized Genetics Education Project, or pgEd, at a congressional briefing titled “Enduring the Extremes: Space Travel, Genetics and Astronaut Health.” This briefing, co-hosted by Rep. Louise Slaughter and Sen. Elizabeth Warren, was motivated by NASA’s goal to conduct landing missions to a(...)

More

Success Follows When Biomedical Engineering and Immunology Collaborate

Posted by  | Perspectives in Research

Kaitlyn Sadtler, a freshly minted Ph.D. from Johns Hopkins’ Cell and Molecular Medicine Graduate Program and Jennifer Elisseeff, Ph.D.,  recently had her thesis work published in Science, where she demonstrated the necessity of the adaptive immune system in fostering a pro-healing response following biomaterial implantation to provide scaffolding for cell growth and tissue repair. Extracellular(...)

More

Scientifically Defining Life

Posted by  | Perspectives in Research

You may expect that defining something as living or dead would be relatively straightforward, yet nearly every scientist you ask for a definition of what constitutes life will give you a different answer, often emphasizing the importance of their area of expertise. Even with widespread disagreement in the details, generally agreed-upon characteristics of life include(...)

More