Perspectives in Research

Johns Hopkins Scientists Discover a Novel Mechanism for β-Lactam Antibiotic Synthesis

Posted by  | Perspectives in Research

Some oft-prescribed antibiotics, including penicillin and cephalosporin, share a common motif in their chemical structure: a small group of atoms arranged in a ring, called a β-lactam. These β-lactam antibiotics utilize this unusual structure to disrupt the cell wall synthesis in bacteria, greatly inhibiting their ability to spread throughout the body. Unfortunately, how these ring(...)

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Can Tasty Food Reduce Stress?

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According to the World Health Organization, more than 1 billion adults in the world are overweight, making them candidates for chronic disease and disability. Many of these people have one thing in common: They unconsciously start eating sweet and high-calorie foods to deal with stress and anxiety. And though later detriments to health may ultimately(...)

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Hopkins MD/PhD student is a Kut above the rest

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While most graduate students are worried about their next exam or an upcoming experiment, Carmen Kut, an M.D./Ph.D. student in the Biomedical Engineering Department at Johns Hopkins School of Medicine, is quietly immersed in her latest endeavors to create meaningful medical products for those in need. Since her time as an undergraduate at Johns Hopkins(...)

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To Reduce Youth Violence, Prescribe a Summer Job

Posted by  | Perspectives in Research

Troubling tales of race, poverty and violence seem to span the contours of today’s media. However, University of Pennsylvania criminologist Sara Heller’s research1, published last month in Science, contributes a hopeful voice to the dialogue. In a randomized controlled trial of disadvantaged youth in Chicago, her study shows a significant link between joblessness and youth(...)

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Early Detection of Colorectal Cancer via MicroRNAs

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Since their discovery in the early 1990s and 2000s, microRNAs have been implicated in a variety of human conditions. Most recently, however, microRNAs are being scrutinized under a different light: not as causative agents in human diseases, but rather as potential guides for cancer detection. The microRNA is a short nucleotide sequence, usually 21 to(...)

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With Disaster Comes Hope

Posted by  | A Day in the Life, Perspectives in Research

On the afternoon of May 12, 2008, a magnitude-8 earthquake hit Sichuan province, a mountainous region in western China. Official figures stated that 69,197 were confirmed dead, including 68,636 in Sichuan province, and 374,176 injured, with 18,222 listed as missing. The earthquake left about 4.8 million people homeless,though the number could have been as high as(...)

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Lessons from the Dr. Oz Senate Appearance

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As 2014 ended, Medscape released “The Year in Medicine 2014: News That Made a Difference.” Among the notable stories were the Dr. Oz Senate hearings, in which the celebrity doctor was censured for “perpetuating weight loss fraud.” He defended himself, saying he believed in his products, though still admitting the products’ claims were not backed(...)

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Scientists Discover Widespread Age-Associated ‘Fingerprints’ in the Human Brain

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An interdisciplinary team of scientists from the Lieber Institute and Johns Hopkins has discovered more than 50,000 regions of the genome that show different levels of activity in the brain across six stages of human development. Their report1, published online on Dec. 15 in Nature Neuroscience, highlights the complexity of genes associated with brain growth(...)

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