Instagram

The Colorful World of Cancer Drug Discovery

The Colorful World of Cancer Drug Discovery

Posted by  | Did You See This?

Melanoma cells stained with PTRF (in red), RPA194 (in green) and nucleus stained in blue. RPA194 is the main subunit of the RNA polymerase I (POL 1) enzyme. Our lab discovered a first-in-class small molecule that inhibits POL 1 enzyme and causes the destruction of RPA194 protein. Here, we are investigating how these proteins are(...)

More

Developing a Laboratory Model for Inclusion Body Myositis

Developing a Laboratory Model for Inclusion Body Myositis

Posted by  | Did You See This?

If you were diagnosed with a disease, there are two questions you would immediately want answered: 1. How can we treat it? 2. What caused the disease? Those two questions are the foundation of my Ph.D. thesis. I study a muscle disease called inclusion body myositis (IBM), which is sometimes referred to as the “Alzheimer’s(...)

More