Cancer

A Novel Cancer Immunotherapy Unveiled: Y-Traps

A Novel Cancer Immunotherapy Unveiled: Y-Traps

Posted by  | Recently Published

The human immune system is composed of a diverse array of cells, which collectively work to exterminate pathogenic entities in the body. Yet this system is able to recognize host, or self, tissues as “friendly” through a variety of so-called immune checkpoint signals. Many cancer types — including melanomas and breast cancers — exploit this(...)

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Using Epigenetics to Fight Tumors

Using Epigenetics to Fight Tumors

Posted by  | Perspectives in Research, Recently Published

While the word cancer treatment may identify everything from chemotherapy to radiation, there is significant variance between the type of cancer and its responsiveness to even the most promising therapies. That has been precisely the case for the α-PD-1 immunotherapy treatment. While it has shown remarkable efficacy in patients diagnosed with lung cancer, other types(...)

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When It Hits Too Close to Home

When It Hits Too Close to Home

Posted by  | A Day in the Life

I am equal parts excited and filled with dread as I open the door. The operating room is abuzz with activity, everyone hurriedly working to complete their duties during the operation. I focus on keeping out of the way of the ordered disorder, and avert my eyes from the patient on the operating table. I(...)

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First Approval of Cancer Immunotherapy Based on Genetic Marker

First Approval of Cancer Immunotherapy Based on Genetic Marker

Posted by  | Recently Published

Immunotherapy is rapidly becoming one of the cornerstones of treatment for several types of cancers, and pembrolizumab, a well-known humanized antibody against the checkpoint inhibitor programmed death 1 (PD-1), is again in the spotlight for new expanded use based on patient's genetic differences. In a first of its kind, the U.S. Food and Drug Administration(...)

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Tasmanian Devils Evolve to Combat Contagious Cancer

Tasmanian Devils Evolve to Combat Contagious Cancer

Posted by  | Perspectives in Research

Australia is home to some of the deadliest creatures on the planet, including venomous snakes, poisonous spiders and hungry sharks. The Tasmanian devil may not be toxic, but the species is known for its vicious behavior. The carnivorous marsupial may look cute and cuddly, but its sharp teeth can take down a kangaroo. Unfortunately, feasting(...)

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